Brian Nicolás Aguirre (born 6 January 2003) is an Argentine footballer who plays as a forward for Primera División club Boca Juniors.
Aguirre joined Newell's Old Boys' youth academy in 2015. He made his first appearance for the senior squad on 26 April 2021 in a 1–2 loss against Gimnasia y Esgrima de La Plata for the Copa de la Liga Profesional. He renewed his contract with the club at the end of the season.
In September 2022, he suffered a knee injury that left him out of the 2022 season.
Aguirre was called up to the Argentina national under-20 football team for the 2022 Maurice Revello Tournament in France.
In January 2023, he was called up to the Argentina national under-20 football team ahead of the 2023 South American Championship.
